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Search Results - biotechnology

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ELM-seq: A novel reporter system to optimize gene expression in vivo in an unbiased and comprehensive manner
Expression level monitoring by DNA methylation and sequencing (ELM-seq) allows optimizing sequence determinants of gene expression and translation comprehensively and more reliably than classical methods.The method can be of special relevance for bioengineering and industrial biotechnology, for the biosynthesis of useful molecules such as drugs, en...
Published: 04/09/2018   |   Inventor(s): Eva Yus, Jae-Seong Yang, Luis Serrano
Keywords(s): Bioengineering, Bioinformatics, Biologics, Biomarkers, Biotechnology, Gene Regulation, Next Generation Sequencing, Protein Expression / Production, Protein Solubility, Vaccines
Category(s): Biotechnology, Methodology
Novel, long-term treatment of Huntington’s disease by gene therapy
Novel synthetic zinc finger proteins delivered to the brain through the use of viral vectors, efficiently and selectively repress the mutant huntingtin gene in a mouse model of Huntington’s disease long term after a single intervention, and successfully restore the motor coordination to levels comparable to those in healthy controls in an acu...
Published: 08/09/2016   |   Inventor(s): Mark Isalan
Keywords(s): Biotechnology, Gene Therapy, Genetic Diseases, Neurodegenerative Diseases, Neuromuscular & Movement Disorders, Neuroscience, Rare / Orphan Diseases
Category(s): Biotechnology, General Biology & Chemistry, Therapeutics (Biologics & Compounds)

 

 

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