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Search Results - protein solubility

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ccSOL omics: large-scale prediction of protein solubility, aggregation and folding
The ccSOL webserver provides large-scale calculations for protein solubility using physical-chemical properties. In addition to the proteome wide identification of soluble fragments on a large scale, ccSOL omics also performs single-point mutations throughout the whole protein sequence to identify susceptible areas. Using information from coil/disorder...
Published: 1/22/2019   |   Inventor(s): Gian Gaetano Tartaglia, Federico Agostini, Davide Cirillo, Riccardo Delli Ponti, Petr Klus
Keywords(s): Algorithms, Bioinformatics, Protein Aggregation and Misfolding, Protein Solubility, Protein Structure & Design, Software
Category(s): Software & Algorithms
ELM-seq: A novel reporter system to optimize gene expression in vivo in an unbiased and comprehensive manner
Expression level monitoring by DNA methylation and sequencing (ELM-seq) allows optimizing sequence determinants of gene expression and translation comprehensively and more reliably than classical methods.The method can be of special relevance for bioengineering and industrial biotechnology, for the biosynthesis of useful molecules such as drugs, enzymes,...
Published: 9/4/2018   |   Inventor(s): Eva Yus, Jae-Seong Yang, Luis Serrano
Keywords(s): Bioengineering, Bioinformatics, Biologics, Biomarkers, Biotechnology, Gene Regulation, Next Generation Sequencing, Protein Expression / Production, Protein Solubility, Vaccines
Category(s): Biotechnology, Methodology




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