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ccSOL omics: large-scale prediction of protein solubility, aggregation and folding
The ccSOL webserver provides large-scale calculations for protein solubility using physical-chemical properties. In addition to the proteome wide identification of soluble fragments on a large scale, ccSOL omics also performs single-point mutations throughout the whole protein sequence to identify susceptible areas. Using information from coil/disorder...
Published: 3/19/2020
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Inventor(s): Gian Gaetano Tartaglia, Federico Agostini, Davide Cirillo, Riccardo Delli Ponti, Petr Klus
Keywords(s): Algorithms, Bioinformatics, Protein Aggregation and Misfolding, Protein Solubility, Protein Structure & Design, Software
Category(s): Software & Algorithms
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FoldX Suite - Protein Design Software
The FoldX Suite builds on the strong fundament of advanced protein design features, already implemented in the successful FoldX, and exploits the power of fragment libraries, by integrating in silico digested backbone protein fragments of different lengths. Such fragment-based strategy allows for new powerful capabilities: loop reconstruction, implemented...
Published: 5/15/2018
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Inventor(s): Luis Serrano, Javier Delgado, François Stricher, Erik Verschueren, Peter Vanhee
Keywords(s): Algorithms, Bioinformatics, Protein Structure & Design, Software
Category(s): Software & Algorithms
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catRAPID: large-scale sequence-based prediction of protein–RNA interactions
catRAPID estimates the binding propensity of protein-RNA pairs by using sequence information only. The algorithm can be used to predict protein associations with coding and non-coding transcripts. Predictions have proved very accurate (> 0.8) when validated by traditional Immunoprecipitation methods, like RIP and CLIP.Applications and Services:Identifies...
Published: 5/25/2020
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Inventor(s): Gian Gaetano Tartaglia, Federico Agostini, Davide Cirillo, Petr Klus
Keywords(s): Algorithms, Bioinformatics, Biomarkers, Genomics, Protein Structure & Design, Software
Category(s): Software & Algorithms
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