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Search Results - epigenetics

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Fast, Low-Input, Easy and Affordable Chromatin ImmunoPrecipitation (FLEA-ChIP)
FLEA-ChIP (Fast, Low-input, Easy and Affordable Chromatin ImmunoPrecipitation) is an efficient, reproducible, and sensitive method for ultra-low input epigenetic profiling, scalable to single cell resolution. FLEA-ChIP has been specifically designed to identify protein-DNA (histone marks and transcription factors) interactions from limiting and degraded...
Published: 10/4/2024   |   Inventor(s): Roderic Guigo, Silvia Perez-Lluch, Marina Ruiz
Keywords(s): Diagnostics, Epigenetics, Personalized Medicine
Category(s): Methodology, Diagnostics & Prognostics, Research Tools (cell lines, mice, kits, ABs, ...)
Novel Therapeutic Targets for DIPG
Various antitumoral targets identified from an unbiased multiomics screen on H3K27M mutated Diffuse Midline Glioma patient-derived material. We are finalizing target validation and developing high throughput small molecule screening assays to develop novel compounds that can be used to treat this devastating childhood cancer. Technology: Diffuse...
Published: 11/21/2024   |   Inventor(s): Luciano Di Croce, Maria Espejo Diaz
Keywords(s): Epigenetics, Oncology, Paediatric Disease
Category(s): Drug Targets & Mechanisms, Therapeutics (Biologics & Compounds)

 

 

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