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Targeting TANGO-1 as a Treatment for Fibrosis (TARTF)
Collagen secretion inhibition in cell and mouse models of fibrosis Compounds that inhibit the formation of the collagen endoplasmic reticulum (ER)-exit machinery in fibroblasts reducing collagen secretion. They can be used for treating fibrotic diseases by targeting the key, common pathological issue, collagen secretion. Technology: Fibrosis underpins...
Published: 11/11/2024   |   Inventor(s): Vivek Malhotra, Ishier Raote, Thomas Krieg, Beate Eckes, Ines Neundorf
Keywords(s): Dermatology, Fibrosis, Respiratory Tract Diseases
Category(s): Drug Targets & Mechanisms, Therapeutics (Biologics & Compounds)

 

 

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